Document Detail


Fibrinolytic therapy for upper-extremity arterial occlusions.
MedLine Citation:
PMID:  2326466     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Acute upper-extremity arterial occlusion may be due to embolic phenomena or de novo thrombosis. If the occlusion is left untreated, claudication or ischemia necessitating amputation can occur. Operative Fogarty-balloon embolectomy has been the treatment of choice for this entity. In a 6-year period the authors used fibrinolysis on nine occasions in eight patients to treat acute upper-extremity arterial occlusions. Concomitant balloon angioplasty was helpful in four cases. Success, defined as a normal hand with at least one artery that was continuously patent to the wrist, was achieved in all patients. A single significant groin hematoma was seen. Neither stroke nor death occurred in any case, and no amputations were necessary. Local transcatheter intraarterial administration of urokinase can be considered a first-line treatment for brachial artery embolus and other causes of acute upper-extremity arterial occlusion.
Authors:
D M Widlus; A C Venbrux; J F Benenati; S E Mitchell; A Lynch-Nyhan; F P Cassidy; F A Osterman
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Radiology     Volume:  175     ISSN:  0033-8419     ISO Abbreviation:  Radiology     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-05-15     Completed Date:  1990-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0401260     Medline TA:  Radiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  393-9     Citation Subset:  AIM; IM    
Affiliation:
Russell H. Morgan Department of Radiology and Radiologic Sciences, Johns Hopkins Medical Institutions, Baltimore, MD 21205-2191.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Angiography
Arm / blood supply*
Axillary Artery / radiography
Brachial Artery / radiography
Embolism / etiology,  radiography,  therapy*
Female
Humans
Male
Middle Aged
Subclavian Artery / radiography
Thrombolytic Therapy* / adverse effects
Thrombosis / etiology,  radiography,  therapy*
Comments/Corrections
Comment In:
Radiology. 1991 Feb;178(2):580-1   [PMID:  1987630 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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