| Fibrinolytic activity in preterm Nigerian babies. | |
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MedLine Citation:
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PMID: 8816039 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Selected variables of the fibrinolytic system were assessed in 55 full-term and 35 preterm neonates along with 70 normal healthy adults as controls. Fibrinogen levels were lower in full- and preterm neonates [2.10 +/- 0.12, and 2.30 +/- 0.18 v. 3.12 +/- 0.12, (P < 0.001)]. There was an increased level of fibrinogen degradation products (FDP) and euglobulin lysis time (ELT) in full- and preterm neonates (7.68 +/- 0.35, 165.94 +/- 7.28, and 5.70 +/- 0.54, 166.10 +/- 9.09, than the adult 5.61 +/- 0.32, 138.43 +/- 3.87, P < 0.001). We conclude that impaired fibrinolytic system might constitute a risk factor for disseminated intravascular coagulation in neonates. |
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Authors:
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A A Famodu |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of tropical pediatrics Volume: 42 ISSN: 0142-6338 ISO Abbreviation: J. Trop. Pediatr. Publication Date: 1996 Aug |
Date Detail:
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Created Date: 1996-10-30 Completed Date: 1996-10-30 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8010948 Medline TA: J Trop Pediatr Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 243-5 Citation Subset: IM |
Affiliation:
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Department of Haematology, Faculty of Medicine, University of Benin, Edo State, Nigeria. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Case-Control Studies Disseminated Intravascular Coagulation / etiology Fibrin Fibrinogen Degradation Products / analysis Fibrinogen / analysis* Humans Infant, Newborn / blood Infant, Premature / blood* Nigeria Risk Factors Serum Globulins / analysis |
| Chemical | |
Reg. No./Substance:
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0/Fibrin Fibrinogen Degradation Products; 0/Serum Globulins; 9001-32-5/Fibrinogen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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