Document Detail

Fibrinolysis in pre-eclamptic toxaemia of pregnancy.
MedLine Citation:
PMID:  5798476     Owner:  NLM     Status:  MEDLINE    
Plasma fibrinolysis is much reduced in normal pregnancy but is the same in women with toxaemia or hypertension, though urinary fibrinolysis is lower in them. The evidence suggests that in toxaemia there must be in addition a slow state of intravascular coagulation. Fibrinolytic inhibitors were found to be normal in this series, though in pregnancy there are raised levels of antitrypsin, alpha(2)-macroglobulin, and beta-lipoprotein. beta-Lipoprotein levels in non-pregnant patients show a correlation with euglobulin lysis times and with inhibitor units.
E N Wardle; I S Menon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  British medical journal     Volume:  2     ISSN:  0007-1447     ISO Abbreviation:  Br Med J     Publication Date:  1969 Jun 
Date Detail:
Created Date:  1969-09-19     Completed Date:  1969-09-19     Revised Date:  2010-10-26    
Medline Journal Info:
Nlm Unique ID:  0372673     Medline TA:  Br Med J     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  625-7     Citation Subset:  AIM; IM    
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MeSH Terms
Antifibrinolytic Agents / analysis
Fibrinogen / analysis
Hypertension / blood
Lipoproteins / blood
Macroglobulins / analysis
Pre-Eclampsia / blood*,  urine
Pregnancy Complications, Cardiovascular / blood
Serum Globulins
Trypsin Inhibitors / blood
Reg. No./Substance:
0/Antifibrinolytic Agents; 0/Lipoproteins; 0/Macroglobulins; 0/Serum Globulins; 0/Trypsin Inhibitors; 9001-32-5/Fibrinogen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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