Document Detail

Fibrin-fibrinogen degradation products in cerebrospinal fluid as an indicator of neonatal brain damage.
MedLine Citation:
PMID:  7324879     Owner:  NLM     Status:  MEDLINE    
The occurrence of brain damage in 57 full term neonates was investigated. The infants were submitted to a prospective protocol involving clinical (neurological and electroencephalographical) and biological examinations, including the determination of the fibrin-fibrinogen degradation products in the blood and cerebrospinal fluid on D1, D3, D8 and D15. Psychomotor events were followed up for a year. Traumatic lumbar taps did not disturb the results significantly. Blood samples were not found to contain noticeable amounts of FDP. Conversely, the existence of FDP in CSF was not infrequent near to delivery and was shown to be closely related to brain damage as evaluated by the psychomotor events.
B Dalens; M J Bezou; M Coulet; E J Raynaud
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  64     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1981 Aug 
Date Detail:
Created Date:  1982-03-13     Completed Date:  1982-03-13     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  81-7     Citation Subset:  IM    
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MeSH Terms
Apgar Score
Birth Injuries / cerebrospinal fluid*
Brain Injuries / cerebrospinal fluid*
Fibrin Fibrinogen Degradation Products / cerebrospinal fluid*
Follow-Up Studies
Infant, Newborn
Reg. No./Substance:
0/Fibrin Fibrinogen Degradation Products

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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