Document Detail

Fibrin sealant for fasciocutaneous flaps.
MedLine Citation:
PMID:  20119899     Owner:  NLM     Status:  MEDLINE    
Fibrin sealant is used in many areas of surgery. We present a novel aspect of flap insetting in the ischial region using fibrin spray to seal the transferred tissue. We analyzed 10 patients suffering from decubital ulcers and assessed drainage output, time of drain removal, as well as complications following fasciocutaneous flap surgery. Patients were randomized to receive sprayed fibrin glue (study group) or not (control group) before wound closure. The mean drainage time was 4 +/- 1 days in the study group and 6 +/- 1 days in the control group ( P = 0.06). The mean drainage volume was 100 +/- 20 mL in the study group and 168 +/- 30 mL in the control group ( P < 0.01). Fibrin sealant led to reduced drainage volumes and duration of drainage, indicating a beneficial effect of the application of fibrin glue in fasciocutaneous flap surgery for pressure sore coverage.
Paolo Erba; Pietro G di Summa; Reto Wettstein; Wassim Raffoul; Daniel F Kalbermatten
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Publication Detail:
Type:  Journal Article; Randomized Controlled Trial     Date:  2010-01-29
Journal Detail:
Title:  Journal of reconstructive microsurgery     Volume:  26     ISSN:  1098-8947     ISO Abbreviation:  J Reconstr Microsurg     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-26     Completed Date:  2010-10-14     Revised Date:  2011-02-16    
Medline Journal Info:
Nlm Unique ID:  8502670     Medline TA:  J Reconstr Microsurg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  IM    
Copyright Information:
(c) Thieme Medical Publishers.
Department of Plastic, Reconstructive and Aesthetic Surgery, University Hospital of Basel, Basel, Switzerland.
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MeSH Terms
Analysis of Variance
Drainage / methods*
Fibrin Tissue Adhesive / therapeutic use*
Follow-Up Studies
Middle Aged
Postoperative Complications / prevention & control
Pressure Ulcer / diagnosis,  surgery*
Reference Values
Risk Assessment
Severity of Illness Index
Skin Transplantation / methods
Surgical Flaps / blood supply*
Treatment Outcome
Wound Healing / physiology
Reg. No./Substance:
0/Fibrin Tissue Adhesive

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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