Document Detail

Fibrillar crystal structure in essential monoclonal IgM kappa cryoglobulinemia.
MedLine Citation:
PMID:  9617499     Owner:  NLM     Status:  MEDLINE    
In monoclonal IgG cryoglobulinemia, two types of crystallization have been demonstrated with electron microscopy at high magnification. In contrast, little information is available on well-defined crystallization in cases of monoclonal IgM cryoglobulinemia. We present a case of pure monoclonal IgM kappa cryoglobulinemia and rapidly progressive glomerulonephritis occurring in a 75-year-old woman. We detected unequivocal formation of fibrillar crystal structure within intraglomerular macrophages on electron microscopy: the structure accords with that in a case of monoclonal IgG cyroglobulinemia described in the literature.
Y Tomiyoshi; T Sakemi; Y Yoshikawa; T Shimokama; T Watanabe
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Clinical nephrology     Volume:  49     ISSN:  0301-0430     ISO Abbreviation:  Clin. Nephrol.     Publication Date:  1998 May 
Date Detail:
Created Date:  1998-08-03     Completed Date:  1998-08-03     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0364441     Medline TA:  Clin Nephrol     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  325-7     Citation Subset:  IM    
Department of Internal Medicine, Saga Medical School, Nabeshima, Japan.
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MeSH Terms
Cryoglobulinemia / pathology*
Glomerulonephritis / complications,  pathology
Immunoglobulin M / analysis*
Immunoglobulin kappa-Chains / analysis*
Kidney Glomerulus / ultrastructure
Macrophages / ultrastructure
Reg. No./Substance:
0/Immunoglobulin M; 0/Immunoglobulin kappa-Chains

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