Document Detail

Fever of unknown origin from a left atrial myxoma: an immunologic basis and cytokine association.
MedLine Citation:
PMID:  21606720     Owner:  NLM     Status:  In-Data-Review    
Myxoma is the most common primary tumor of the heart. The typical presentations include a triad of embolic phenomena, intracardiac flow obstruction, and constitutional symptoms. We report a case of cardiac myxoma presenting as prolonged fever. Leukocytosis with a left shift, anemia, and elevated C-reactive protein were noted. A large left atrial myxoma was found incidentally by chest computed tomography. The fever subsided after surgical removal of the myxoma. His elevated serum interleukin-4 (IL-4), IL-6, IL-12 p70, interferon-γ, and tumor necrosis factor-α returned to undetectable levels four days after surgery. Cardiac myxomas should be included in the differential diagnosis of prolonged fever, even though no typical symptoms could be found.
Jiun-Nong Lin; Chung-Hsu Lai; Li-Fen Lu; Hsi-Hsun Lin
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Southern medical journal     Volume:  104     ISSN:  1541-8243     ISO Abbreviation:  South. Med. J.     Publication Date:  2011 May 
Date Detail:
Created Date:  2011-05-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0404522     Medline TA:  South Med J     Country:  United States    
Other Details:
Languages:  eng     Pagination:  360-2     Citation Subset:  AIM; IM    
From the Department of Critical Care Medicine, Division of Infectious Diseases, and Division of Cardiovascular Surgery, E-Da Hospital/I-Shou University; and Graduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
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