Document Detail


Fever effects and treatment in critical care: Literature review.
MedLine Citation:
PMID:  23199670     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Considering that the incidence of fever may reach up to 75% among critically ill adults, healthcare professionals employed in the Intensive Care Unit (ICU) are called to evaluate and manage patient temperature elevation on a daily basis. This literature review synthesizes the evidence about the effects of fever and antipyretic treatment in ICU patients. Although the febrile response acts protectively against infections, noxious effects are possible for patients with cerebral damage, neuropsychiatric disorders or limited cardiorespiratory reserve. Observational studies on ICU populations have reported associations between fever magnitude and patient mortality. Especially recent findings indicated that infected patients may significantly benefit from temperature elevation, while high fever may be maladaptive for non-infected ones. Aggressive antipyretic treatment of ICU patients has not been followed by decreased mortality in randomized trials. However, fever suppression and return to normothermia improved outcomes of septic shock patients. Antipyretic treatment should begin with drug administration and proceed with external cooling in case of refractory fever, but adverse effects of both antipyretic methods should always be considered. This article concludes by providing implications for antipyretic treatment of critically ill adults and suggesting areas for future research.
Authors:
Panagiotis Kiekkas; Diamanto Aretha; Nick Bakalis; Irini Karpouhtsi; Chris Marneras; George I Baltopoulos
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-28
Journal Detail:
Title:  Australian critical care : official journal of the Confederation of Australian Critical Care Nurses     Volume:  -     ISSN:  1036-7314     ISO Abbreviation:  Aust Crit Care     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-12-3     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9207852     Medline TA:  Aust Crit Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier Ltd.
Affiliation:
Nursing Department, Highest Technological Educational Institute of Patras, Patras, Greece. Electronic address: kiekkpan@otenet.gr.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Pitfalls in image guided tissue sampling in the head and neck.
Next Document:  Impact of country of birth on arterial function in subjects living in France.