Document Detail

Fetoscopic Laser Therapy for Twin-Twin Transfusion Syndrome Before 17 and After 26 Weeks Gestation.
MedLine Citation:
PMID:  23178244     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To compare perinatal outcomes of pregnancies undergoing "early" (<17 wks) or "late" (>26 wks) fetoscopic laser ablation of placental vascular anastomoses for twin-twin transfusion syndrome (TTTS) to "conventional" cases treated between 17-26 wks gestation. STUDY DESIGN: Single center, retrospective analysis of 325 consecutive pregnancies which underwent fetoscopic laser therapy for severe TTTS. RESULTS: Twenty-four "early", 18 "late" and 283 "conventional" pregnancies with severe TTTS underwent, laser therapy. Fetoscopy duration, gestation at delivery, survival rate and complications were comparable between groups, except for preterm premature rupture of membranes <7 days after laser, which was more common in the "early" group than in either of the other two groups. CONCLUSION: Laser therapy for TTTS <17 wks or >26 wks gestation has similar outcomes to procedures done at 17-26 wks. We suggest that conventional gestational age guidelines of 16-26 wks for laser therapy for TTTS should be re-evaluated.
David Baud; Rory Windrim; Johannes Keunen; Edmond N Kelly; Prakesh Shah; Tim Van Mieghem; Gareth R Seaward; Greg Ryan
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Publication Detail:
Type:  EDITORIAL     Date:  2012-11-21
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  -     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.
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