Document Detail

Fetoneonatal hydrops from human parvovirus B19. Case report.
MedLine Citation:
PMID:  7823267     Owner:  NLM     Status:  MEDLINE    
Authors report the case of a newborn who died just a few hours after the birth as a result of intrauterine Parvovirus B19 infection. Diagnosis of fetal hydrops was made by ultrasound examination at the 25th week of pregnancy. Etiology was established on the basis of specific antibody findings in the serum of the mother, the fetus (by cordocentesis), and the neonate; B19 virus was then observed in the fetus and the neonate tissues after death using the dot-blot hybridization assay and the polymerase chain reaction technique for viral DNA. The severe fetal anemia was treated with intrauterine transfusions, but achieved poor results. The pathogenesis of fetal hydrops and advisability of intrauterine treatment in such cases are discussed.
C Panero; A Azzi; C Carbone; M Pezzati; G Mainardi; S di Lollo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  22     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  1994  
Date Detail:
Created Date:  1995-02-16     Completed Date:  1995-02-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  257-64     Citation Subset:  IM    
Department of Pediatrics, University of Florence, Italy.
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MeSH Terms
Hydrops Fetalis / pathology,  virology*
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases / pathology,  virology*
Parvoviridae Infections / complications*,  pathology
Parvovirus B19, Human*

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