Document Detail

Fetomaternal transplacental hemorrhage during pregnancy and after delivery.
MedLine Citation:
PMID:  3095989     Owner:  NLM     Status:  MEDLINE    
One third of very weakly Rh-immunized women show no increase in their level of Rh immunization during pregnancy and after delivery. Administration of 300 micrograms of Rh immune globulin at 6-week intervals does not alter the incidence of lack of progression of Rh immunization in such women. Thirty-three Rh-positive women who ultimately delivered ABO-compatible babies, had Kleihauer fetal transplacental hemorrhage (TPH) screening tests carried out at 2-week intervals during pregnancy and shortly after delivery. One third of the 33 women had no detectable TPH or a TPH of 0.01 ml of fetal red cells. We conclude that one third of weakly Rh-immunized women failed to show any progression of their Rh immune response during pregnancy or after delivery because they were exposed to too few fetal red cells (0.01 ml or less) to produce such a response.
J M Bowman; J M Pollock; L E Penston
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Vox sanguinis     Volume:  51     ISSN:  0042-9007     ISO Abbreviation:  Vox Sang.     Publication Date:  1986  
Date Detail:
Created Date:  1986-11-26     Completed Date:  1986-11-26     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0413606     Medline TA:  Vox Sang     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  117-21     Citation Subset:  IM    
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MeSH Terms
ABO Blood-Group System / immunology
Blood Group Incompatibility / blood
Cross-Sectional Studies
Delivery, Obstetric*
Erythrocytes / immunology
Fetal Blood / cytology
Gestational Age
Immunization, Passive
Maternal-Fetal Exchange*
Pregnancy / blood*,  immunology
Rh Isoimmunization / immunology
Reg. No./Substance:
0/ABO Blood-Group System

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