Document Detail

Fetomaternal hemorrhage after midtrimester genetic amniocentesis at King Chulalongkorn Memorial Hospital.
MedLine Citation:
PMID:  10659542     Owner:  NLM     Status:  MEDLINE    
Midtrimester genetic amniocentesis has become an accepted part of modern obstetric care. Although its accuracy is well established, the risk of fetomaternal hemorrhage remains controversial. This prospective study was conducted to determine how effective continuous ultrasound guided amniocentesis is in preventing fetomaternal hemorrhage. The authors investigated 30 patients undergoing midtrimester genetic amniocentesis at our institution. Amniocentesis was performed under continuous real-time ultrasound guidance using a 21-gauge, 3.5-inch long spinal needle. Maternal serum alpha-fetoprotein (AFP) levels were determined before, at 5 minutes and at 1 hour after amniocentesis. There were no significant changes in maternal serum AFP levels either at 5 minutes or at 1 hour after amniocentesis. Midtrimester genetic amniocentesis performed by a trained and experienced operator under continuous ultrasound guidance does not significantly increase the risk of fetomaternal hemorrhage after the procedure.
Y Tannirandorn; O Romayanan
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of the Medical Association of Thailand = Chotmaihet thangphaet     Volume:  82     ISSN:  0125-2208     ISO Abbreviation:  J Med Assoc Thai     Publication Date:  1999 Nov 
Date Detail:
Created Date:  2000-02-18     Completed Date:  2000-02-18     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7507216     Medline TA:  J Med Assoc Thai     Country:  THAILAND    
Other Details:
Languages:  eng     Pagination:  1089-93     Citation Subset:  IM    
Department of Anatomy, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
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MeSH Terms
Amniocentesis / adverse effects*
Fetomaternal Transfusion / etiology*
Middle Aged
Pregnancy Trimester, Second
Prospective Studies
alpha-Fetoproteins / analysis
Reg. No./Substance:

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