Document Detail

Feto-fetal transfusion syndrome in monochorionic quadruplets.
MedLine Citation:
PMID:  20093884     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Endoscopic laser ablation of placental vessels is now the preferred treatment for severe feto-fetal transfusion syndrome in twin gestations, and has been well-documented in triplet gestations as well. CASE: Stage IV feto-fetal transfusion syndrome was diagnosed at 20.3 weeks of gestation between two of a set of monochorionic, tetramniotic quadruplets. Endoscopic laser ablation occurred at 20.4 weeks. Feto-fetal transfusion recurred at 22 weeks between the initial donor and the two previously unaffected fetuses. Delivery occurred at 24.9 weeks. The donor and one of the corecipients died shortly after birth. The sole survivor was doing well. CONCLUSION: Treatment of feto-fetal transfusion syndrome in higher-order gestations is challenging because of the increased pregnancy risks, the difficult angioarchitecture and the risk of recurrence.
Barbara M O'Brien; Helen M Feltovich; Stephen R Carr; Francois I Luks
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  115     ISSN:  1873-233X     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-01-22     Completed Date:  2010-05-26     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  470-2     Citation Subset:  AIM; IM    
Fetal Treatment Program, Division of Maternal-Fetal Medicine, Alpert Medical School of Brown University, Providence, Rhode Island 02903, USA.
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MeSH Terms
Fetal Death
Fetofetal Transfusion / surgery*
Laser Therapy*
Pregnancy Trimester, Second
Premature Birth

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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