| Fetal umbilical artery Doppler in small preterms: (IQ) Neurocognitive outcome at five years of age. | |
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MedLine Citation:
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PMID: 23331087 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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AIM: To investigate if absent or reversed end-diastolic flow in the umbilical artery (AREDF) is associated with neonatal mortality, morbidity or long-term neurocognitive outcome in extremely preterm infants exposed to preeclampsia or intrauterine growth restriction. METHODS: Prenatal Doppler data were retrospectively collected for liveborn infants with gestational age (GA) <28 weeks or birth weight (BW) <1000 g, born small for gestational age (SGA- BW <5(th) percentile for GA) or of mothers with preeclampsia at the four largest university hospitals in Norway during 1999-2000. Neonatal mortality and morbidities, cerebral palsy (CP) and IQ at 5 years of age were compared for infants with or without AREDF. RESULTS: Of 260 infants, 84 were eligible and 71 of them had sufficient Doppler data. Of these, 38 (54%) had AREDF. Of 33 infants born <28 weeks, 7/19 (37%) with AREDF and none of 14 without AREDF had severe cerebral haemorrhage (SCH) (p=0.01). AREDF was not significantly associated with mortality, other NICU morbidities, CP or reduced IQ. For the 38 infants with GA ≥28 weeks AREDF (19/38) was not associated with adverse outcomes. CONCLUSION: AREDF was associated with increased risk of SCH in extremely preterm infants (GA <28 weeks). ©2013 The Author(s)/Acta Paediatrica ©2013 Foundation Acta Paediatrica. |
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Authors:
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Siw Helen W Eger; Kristian Sommerfelt; Torvid Kiserud; Trond Markestad |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2013-1-17 |
Journal Detail:
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Title: Acta paediatrica (Oslo, Norway : 1992) Volume: - ISSN: 1651-2227 ISO Abbreviation: Acta Paediatr. Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2013-1-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9205968 Medline TA: Acta Paediatr Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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©2013 The Author(s)/Acta Paediatrica ©2013 Foundation Acta Paediatrica. |
Affiliation:
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Department of Clinical Medicine, University of Bergen, Norway; Department of Pediatrics, Haukeland University Hospital, Norway. |
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