| Fetal thyrotoxicosis in utero. | |
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MedLine Citation:
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PMID: 435593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A case of fetal thyrotoxicosis in utero in a boy with familial predisposition to thyrotoxicosis is reported. At 26 weeks of gestation fetal hyperkinesia and fetal tachycardia developed. This was preceded by a significant pathologic increase in long-acting thyroid stimulator (LATS) in the mother. The fetal hyperkinesia and tachycardia were considered to be signs of fetal thyrotoxicosis, possibly induced by placentally transferred LATS. The fetal thyrotoxicosis responded well to propylthiouracil given to the mother. After birth the boy developed slight signs of neonatal thyrotoxicosis although his serum thyroxine values increased analogous to those of his elder sister, who had presented classical neonatal thyrotoxicosis. |
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Authors:
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J Serup; S Petersen |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Biology of the neonate Volume: 35 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 1979 |
Date Detail:
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Created Date: 1979-07-16 Completed Date: 1979-07-16 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 175-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Diseases / drug therapy, genetics Humans Hyperkinesis / etiology Hyperthyroidism / congenital*, drug therapy, genetics Infant, Newborn Long-Acting Thyroid Stimulator / blood Male Maternal-Fetal Exchange Pregnancy Propylthiouracil / therapeutic use Tachycardia / etiology Thyroxine / blood |
| Chemical | |
Reg. No./Substance:
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51-52-5/Propylthiouracil; 7488-70-2/Thyroxine; 9034-48-4/Long-Acting Thyroid Stimulator |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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