| Fetal thyroid in two-dimensional ultrasonography: nomograms according to gestational age and biparietal diameter. | |
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MedLine Citation:
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PMID: 22445205 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To establish fetal thyroid nomograms based on gestational age and biparietal diameter and to compare obtained results with previously published data. STUDY DESIGN: A cross-sectional study of 241 healthy pregnant women at 14-38 week of gestation was undertaken. Exclusion criteria were: known maternal thyroid or systemic disease, unknown date of last menstrual period, multiple pregnancy and fetal malformations. Fetal thyroid diameter (FTD), circumference (FTC) and area (FTA) were measured by two-dimensional ultrasonography and plotted against gestational age (GA) and biparietal diameter (BPD). RESULTS: FTD, FTC and FTA increased logarithmically to GA and BPD. Fetal thyroid measurements as a function of GA were expressed by logarithmic formulas: ln(FTD)=3.6025-23.0315/GA, ln(FTC)=4.6227-22.8003/GA, ln(FTA)=6.6303-45.0831/GA. The following logarithmic formulas were obtained for fetal thyroid measurements according to BPD: ln(FTD)=3.4068-45.4271/BPD, ln(FTC)=4.4271-44.8359/BPD, ln(FTA)=6.2390-88.4408/BPD. There were highly significant correlations between thyroid measurements and GA or BPD: r=0.87-0.90, p<0.00001. CONCLUSIONS: We have established age-dependent and age-independent nomograms of fetal thyroid. These nomograms will enable prenatal diagnosis in fetuses at risk of thyroid disorders. |
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Authors:
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Małgorzata Gietka-Czernel; Marzena Dębska; Piotr Kretowicz; Romuald Dębski; Wojciech Zgliczyński |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-3-23 |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: - ISSN: 1872-7654 ISO Abbreviation: - Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-3-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2012 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Endocrinology, Medical Center of Postgraduate Education, Warsaw, Poland. |
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