Document Detail

Fetal thyroid in two-dimensional ultrasonography: nomograms according to gestational age and biparietal diameter.
MedLine Citation:
PMID:  22445205     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To establish fetal thyroid nomograms based on gestational age and biparietal diameter and to compare obtained results with previously published data. STUDY DESIGN: A cross-sectional study of 241 healthy pregnant women at 14-38 week of gestation was undertaken. Exclusion criteria were: known maternal thyroid or systemic disease, unknown date of last menstrual period, multiple pregnancy and fetal malformations. Fetal thyroid diameter (FTD), circumference (FTC) and area (FTA) were measured by two-dimensional ultrasonography and plotted against gestational age (GA) and biparietal diameter (BPD). RESULTS: FTD, FTC and FTA increased logarithmically to GA and BPD. Fetal thyroid measurements as a function of GA were expressed by logarithmic formulas: ln(FTD)=3.6025-23.0315/GA, ln(FTC)=4.6227-22.8003/GA, ln(FTA)=6.6303-45.0831/GA. The following logarithmic formulas were obtained for fetal thyroid measurements according to BPD: ln(FTD)=3.4068-45.4271/BPD, ln(FTC)=4.4271-44.8359/BPD, ln(FTA)=6.2390-88.4408/BPD. There were highly significant correlations between thyroid measurements and GA or BPD: r=0.87-0.90, p<0.00001. CONCLUSIONS: We have established age-dependent and age-independent nomograms of fetal thyroid. These nomograms will enable prenatal diagnosis in fetuses at risk of thyroid disorders.
Małgorzata Gietka-Czernel; Marzena Dębska; Piotr Kretowicz; Romuald Dębski; Wojciech Zgliczyński
Related Documents :
2772555 - Characterization of hemoglobin variants. prenatal diagnosis on a fetus at risk of havin...
6177235 - Fetal hemoglobin: optimum conditions for its estimation by alkali denaturation.
10923245 - Paradoxical effects of exogenous proteins on lung function in surfactant-deficient rats.
22742605 - The effects of iodine deficiency in pregnancy and infancy.
7189265 - Diurnal variation of fetal activity.
23288385 - Complex challenges in treating depression during pregnancy.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-3-23
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  -     ISSN:  1872-7654     ISO Abbreviation:  -     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-3-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.
Department of Endocrinology, Medical Center of Postgraduate Education, Warsaw, Poland.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Why thioridazine in combination with antibiotics cures extensively drug-resistant Mycobacterium tube...
Next Document:  Pre-operative systemic inflammatory response markers in predicting lymph node metastasis in endometr...