| Fetal surgery for myelomeningocele. | |
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MedLine Citation:
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PMID: 22682379 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Myelomeningocele (MMC) is a congenital neural tube defect that occurs in approximately 1 in 2900 live births in the United States. It is a devastating disability with significant morbidity and mortality within the first few decades of life. MMC was the first nonlethal disease to be considered and studied for fetal surgery and is now the most common open fetal surgery performed. The recently completed MOMS randomized controlled trial has shown that fetal repair for MMC can improve hydrocephalus and hindbrain herniation, can reduce the need for vetriculoperitoneal shunting, and may improve distal neurologic function in some patients. |
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Authors:
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Payam Saadai; Diana L Farmer |
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Publication Detail:
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Type: Journal Article; Review Date: 2012-05-15 |
Journal Detail:
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Title: Clinics in perinatology Volume: 39 ISSN: 1557-9840 ISO Abbreviation: Clin Perinatol Publication Date: 2012 Jun |
Date Detail:
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Created Date: 2012-06-11 Completed Date: 2013-01-11 Revised Date: 2013-04-16 |
Medline Journal Info:
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Nlm Unique ID: 7501306 Medline TA: Clin Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 279-88 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Pediatric Surgery, Department of Surgery, Fetal Treatment Center, University of California, San Francisco, 513 Parnassus Avenue, HSW 16-01, Box 0570, San Francisco, CA 94143-0570, USA. payam.saadai@ucsfmedctr.org |
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| MeSH Terms | |
Descriptor/Qualifier:
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Female Fetal Diseases / surgery Fetoscopy / methods* Fetus / physiopathology, surgery* Humans Hydrocephalus / surgery* Meningomyelocele / physiopathology, surgery* Pregnancy Pregnancy Complications / surgery* Treatment Outcome Ventriculoperitoneal Shunt* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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