Document Detail


Fetal surgery for myelomeningocele.
MedLine Citation:
PMID:  22682379     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Myelomeningocele (MMC) is a congenital neural tube defect that occurs in approximately 1 in 2900 live births in the United States. It is a devastating disability with significant morbidity and mortality within the first few decades of life. MMC was the first nonlethal disease to be considered and studied for fetal surgery and is now the most common open fetal surgery performed. The recently completed MOMS randomized controlled trial has shown that fetal repair for MMC can improve hydrocephalus and hindbrain herniation, can reduce the need for vetriculoperitoneal shunting, and may improve distal neurologic function in some patients.
Authors:
Payam Saadai; Diana L Farmer
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Publication Detail:
Type:  Journal Article; Review     Date:  2012-05-15
Journal Detail:
Title:  Clinics in perinatology     Volume:  39     ISSN:  1557-9840     ISO Abbreviation:  Clin Perinatol     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-06-11     Completed Date:  2013-01-11     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  7501306     Medline TA:  Clin Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  279-88     Citation Subset:  IM    
Copyright Information:
Copyright © 2012 Elsevier Inc. All rights reserved.
Affiliation:
Division of Pediatric Surgery, Department of Surgery, Fetal Treatment Center, University of California, San Francisco, 513 Parnassus Avenue, HSW 16-01, Box 0570, San Francisco, CA 94143-0570, USA. payam.saadai@ucsfmedctr.org
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MeSH Terms
Descriptor/Qualifier:
Female
Fetal Diseases / surgery
Fetoscopy / methods*
Fetus / physiopathology,  surgery*
Humans
Hydrocephalus / surgery*
Meningomyelocele / physiopathology,  surgery*
Pregnancy
Pregnancy Complications / surgery*
Treatment Outcome
Ventriculoperitoneal Shunt*
Grant Support
ID/Acronym/Agency:
U10 HD041669/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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