Document Detail

Fetal splenic rupture following transfusion.
MedLine Citation:
PMID:  11336767     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Splenic rupture in the newborn is a rare complication in erythroblastosis fetalis. There are no reports of splenic rupture in the fetus affected by hemolytic disease of the newborn. CASE: A 41-year-old gravida 3, para 2-0-0-2 with severe rhesus alloimmunization was managed with serial intrauterine transfusions resulting in fetal death after the fourth procedure. Autopsy findings revealed intra-abdominal clotted blood and splenic capsular defects consistent with splenic rupture. CONCLUSION: Fetal splenic rupture might occur in hemolytic disease of the newborn associated with splenomegaly. Acute hemodynamic changes with increased intra-abdominal pressure from intrauterine transfusion might precipitate splenic rupture. (Obstet Gynecol 2001;97:824-5.
P W Whitecar; N D Depcik-Smith; R A Strauss; K J Moise
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  97     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2001 May 
Date Detail:
Created Date:  2001-05-04     Completed Date:  2001-05-24     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  824-5     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2001 by The American College of Obstetricians and Gynecologists.)
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, 214 MacNider Building, CB#7516, Chapel Hill, NC 27599-7516, USA.
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MeSH Terms
Blood Transfusion, Intrauterine / adverse effects*
Erythroblastosis, Fetal / therapy*
Fetal Death
Pregnancy Complications, Hematologic / therapy*
Prenatal Care
Rh Isoimmunization / therapy*
Rupture, Spontaneous
Splenomegaly / etiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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