| Fetal splenic rupture following transfusion. | |
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MedLine Citation:
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PMID: 11336767 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Splenic rupture in the newborn is a rare complication in erythroblastosis fetalis. There are no reports of splenic rupture in the fetus affected by hemolytic disease of the newborn. CASE: A 41-year-old gravida 3, para 2-0-0-2 with severe rhesus alloimmunization was managed with serial intrauterine transfusions resulting in fetal death after the fourth procedure. Autopsy findings revealed intra-abdominal clotted blood and splenic capsular defects consistent with splenic rupture. CONCLUSION: Fetal splenic rupture might occur in hemolytic disease of the newborn associated with splenomegaly. Acute hemodynamic changes with increased intra-abdominal pressure from intrauterine transfusion might precipitate splenic rupture. (Obstet Gynecol 2001;97:824-5. |
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Authors:
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P W Whitecar; N D Depcik-Smith; R A Strauss; K J Moise |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Obstetrics and gynecology Volume: 97 ISSN: 0029-7844 ISO Abbreviation: Obstet Gynecol Publication Date: 2001 May |
Date Detail:
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Created Date: 2001-05-04 Completed Date: 2001-05-24 Revised Date: 2009-10-26 |
Medline Journal Info:
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Nlm Unique ID: 0401101 Medline TA: Obstet Gynecol Country: United States |
Other Details:
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Languages: eng Pagination: 824-5 Citation Subset: AIM; IM |
Copyright Information:
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Copyright 2001 by The American College of Obstetricians and Gynecologists.) |
Affiliation:
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Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, 214 MacNider Building, CB#7516, Chapel Hill, NC 27599-7516, USA. paul_whitecar@med.unc.edu |
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Blood Transfusion, Intrauterine / adverse effects* Erythroblastosis, Fetal / therapy* Female Fetal Death Humans Pregnancy Pregnancy Complications, Hematologic / therapy* Prenatal Care Rh Isoimmunization / therapy* Rupture, Spontaneous Splenomegaly / etiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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