Document Detail

Fetal spine morphology and maturation during the second trimester. Sonographic evaluation.
MedLine Citation:
PMID:  3316699     Owner:  NLM     Status:  MEDLINE    
We reviewed high-resolution real-time sonographic images (especially selected for a lack of technical artifacts) of the fetal spine of 46 normal fetuses between 18-27 menstrual weeks of development. The degree of visible posterior neural arch ossification was graded and compared with the gestational age. Recognizable early ossification of the laminae was seen in the cervical region of all fetuses studied. Similar ossification followed sequentially in the thoracic, lumbar, and sacral regions; however, sonographically recognizable ossification of the laminae in the lumbar spine was delayed until 22-24 weeks and in the sacral spine until 25 weeks or more. Awareness of these features will help to prevent false-positive diagnoses of dysraphism and, conversely, hopefully augment our ability to detect such lesions.
R A Filly; G F Simpson; G Linkowski
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  6     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1987 Nov 
Date Detail:
Created Date:  1988-01-14     Completed Date:  1988-01-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  631-6     Citation Subset:  IM    
Department of Radiology, University of California School of Medicine, San Francisco 94143.
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MeSH Terms
Neural Tube Defects / pathology*
Pregnancy Trimester, Second
Prenatal Diagnosis*
Spine / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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