Document Detail

Fetal salvage in maternal systemic lupus erythematosus.
MedLine Citation:
PMID:  8257074     Owner:  NLM     Status:  MEDLINE    
Fifty-two pregnancies in 30 patients with systemic lupus erythematosus were studied prospectively. There were two spontaneous abortions, two therapeutic terminations for active disease, two intrauterine deaths before 28 weeks and one stillbirth. Forty-five (86.6%) pregnancies had a successful outcome. Five patients had renal involvement before or during pregnancy whilst 12 (23%) had preeclampsia. Placental insufficiency and intrauterine hypoxia contributed to a high Caesarean section rate (44%). The selection of patients for pregnancy, optimal medical care, antenatal monitoring and intensive neonatal care have improved fetal salvage in this condition.
R L TambyRaja
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Annals of the Academy of Medicine, Singapore     Volume:  22     ISSN:  0304-4602     ISO Abbreviation:  Ann. Acad. Med. Singap.     Publication Date:  1993 Jul 
Date Detail:
Created Date:  1994-01-11     Completed Date:  1994-01-11     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7503289     Medline TA:  Ann Acad Med Singapore     Country:  SINGAPORE    
Other Details:
Languages:  eng     Pagination:  634-7     Citation Subset:  IM    
Department of Obstetrics & Gynaecology, National University Hospital.
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MeSH Terms
Abortion, Spontaneous / etiology*
Azathioprine / administration & dosage
Fetal Death / etiology*
Infant, Newborn
Kidney Function Tests
Lupus Erythematosus, Systemic / diagnosis*,  drug therapy
Pre-Eclampsia / diagnosis
Prednisolone / administration & dosage
Pregnancy Complications / diagnosis*,  drug therapy
Pregnancy Outcome
Prospective Studies
Reg. No./Substance:
446-86-6/Azathioprine; 50-24-8/Prednisolone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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