Document Detail


Fetal respiratory distress causing CNS and inner ear hemorrhage.
MedLine Citation:
PMID:  642671     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fifty-two consecutive temporal bones of infants who died neonatally, or in utero of natural causes, were studied. Complete autopsies were performed. Twenty-eight infants had a variety of pulmonary disorders which resulted in severe respiratory distress prior to their death. Of these, the majority had bleeding intracranially and into the inner ear. There were five major pathways of central nervous system and subarachnoid hemorrhage involvement of the inner ear: 1) the modiolus, 2) cochlear aqueduct, 3) retrograde via the cochlear vein, 4) episodes of spontaneous bleeding into various compartments of the inner ear, and 4) hemorrhage via the otic capsule. The remaining 24 infants died of other natural causes. Two had CNS bleeding with no extension to the inner ear. We propose that there is a syndrome which consists of 1) neonatal respiratory distress, 2) intracranial hemorrhage, and 3) bleeding into the inner ear--an extension of a subarachnoid or subependymal matrix bleeding diathesis.
Authors:
G J Spector; W J Pettit; G Davis; M Strauss; E Rauchbach
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Laryngoscope     Volume:  88     ISSN:  0023-852X     ISO Abbreviation:  Laryngoscope     Publication Date:  1978 May 
Date Detail:
Created Date:  1978-06-28     Completed Date:  1978-06-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8607378     Medline TA:  Laryngoscope     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  764-84     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cerebral Hemorrhage / etiology*,  pathology
Ear, Inner / pathology
Female
Fetal Diseases / complications*,  pathology
Hemorrhage / etiology*,  pathology
Humans
Infant
Infant, Newborn
Labyrinth Diseases / etiology*,  pathology
Lung / pathology
Male
Pregnancy
Respiratory Distress Syndrome, Newborn / complications*,  pathology
Subarachnoid Hemorrhage / etiology
Syndrome

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