Document Detail

Fetal pulmonary valvuloplasty for critical pulmonary stenosis or atresia with intact septum.
MedLine Citation:
PMID:  12443597     Owner:  NLM     Status:  MEDLINE    
Progressive stenosis of the semilunar valves in utero can be life threatening. We treated two fetuses with complete or almost complete pulmonary atresia and imminent hydrops (increased cardiothoracic ratio, pericardial effusion, holosystolic tricuspid regurgitation extending into diastole, and abnormal venous Dopplers). We dilated the pulmonary valve of two fetuses in utero at 28 and 30 weeks' gestation, through the mothers' abdomens. After the procedure, the fetuses had decreased signs of circulatory failure and gestation continued until near term. In the neonatal period, we did a repeat valvuloplasty with systemic-to-pulmonary arterial shunt. Both children (now aged 18 months and 12 months) now have biventricular circulation. Surgery on selected fetuses with semilunar valve stenosis or atresia, or both, can extend pregnancy and favourably change the postnatal surgical options.
Gerald Tulzer; Wolfgang Arzt; Rodney C G Franklin; Pamela V Loughna; Rudi Mair; Helena M Gardiner
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Lancet     Volume:  360     ISSN:  0140-6736     ISO Abbreviation:  Lancet     Publication Date:  2002 Nov 
Date Detail:
Created Date:  2002-11-21     Completed Date:  2002-12-09     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  2985213R     Medline TA:  Lancet     Country:  England    
Other Details:
Languages:  eng     Pagination:  1567-8     Citation Subset:  AIM; IM    
Children's Heart Centre Linz, Children's Hospital of Linz, Austria.
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MeSH Terms
Balloon Dilatation*
Fetal Diseases / therapy*
Pulmonary Atresia / therapy*
Pulmonary Valve*
Pulmonary Valve Stenosis / therapy*
Treatment Outcome

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