Document Detail

Fetal pulmonary maturity: relationship between optical density (650 nm) to the lecithin/sphingomyelin ratio and phosphatidylglycerol in amniotic fluid.
MedLine Citation:
PMID:  6139307     Owner:  NLM     Status:  MEDLINE    
An optical density value greater than or equal to 0.15 at A650 n m of amniotic fluid obtained through transabdominal amniocentesis from a high risk obstetrical population, which excluded diabetes mellitus, isoimmunization, and amniotic fluid infection, correlated 98.6% with a mature lecithin to sphingomyelin ratio (L/S) greater than or equal to 2.0% and 41.6% with the presence of phosphatidylglycerol (PG). The corresponding false positive rates were 1.4% and 16.8%, respectively. In 30 infants delivered within 48 h of testing, A650 n m greater than or equal to 0.15 correlated 100% with absence of respiratory distress syndrome. A650 n m is not recommended for Rhesus immunized gestations, diabetic pregnancies and amniotic fluid infection due to a high false positive rate with A650 nm compared to L/S and PG.
S Moodley; J H Liu; R C Cherkis; R K Miller; T A Merrit; L E Whalen
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  21     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1984-01-27     Completed Date:  1984-01-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  IM    
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MeSH Terms
Amniotic Fluid / analysis,  physiology*
Fetal Membranes, Premature Rupture / physiopathology
Fetal Organ Maturity
Infant, Newborn
Lung / embryology*
Phosphatidylcholines / analysis*
Phosphatidylglycerols / analysis*
Respiratory Distress Syndrome, Newborn / diagnosis
Retrospective Studies
Sphingomyelins / analysis*
Reg. No./Substance:
0/Phosphatidylcholines; 0/Phosphatidylglycerols; 0/Sphingomyelins

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