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Fetal and perinatal consequences of maternal obesity.
MedLine Citation:
PMID:  20530101     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
In many industrialised countries, one in five women booking for antenatal care is obese. As well as affecting maternal health, maternal obesity may have important adverse consequences for fetal, neonatal and long-term health and well-being. Maternal obesity is associated with a higher risk of stillbirth, elective preterm birth and perinatal mortality. The incidence of severe birth defects, particularly neural tube and structural cardiac defects, appears to be higher in infants of obese mothers. Fetal macrosomia associated with maternal obesity and gestational diabetes predisposes infants to birth injuries, perinatal asphyxia and transitional problems such as neonatal respiratory distress and metabolic instability. Maternal obesity may also result in long-term health problems for offspring secondary to perinatal problems and to intrauterine and postnatal programming effects. Currently, the available interventions to prevent and treat maternal obesity are of limited proven utility and further research is needed to define the effects of maternal weight management interventions on fetal and neonatal outcomes.
Authors:
Chakrapani Vasudevan; Mary Renfrew; William McGuire
Publication Detail:
Type:  Journal Article     Date:  2010-06-07
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  96     ISSN:  1468-2052     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-12     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  F378-82     Citation Subset:  AIM; IM    
Affiliation:
Centre for Reviews and Dissemination, Hull York Medical School, University of York, York YO10 5DD, UK; william.mcguire@hyms.ac.uk.
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