Document Detail

Fetal and neonatal effects of the beta-adrenoceptor blocking agents.
MedLine Citation:
PMID:  2886298     Owner:  NLM     Status:  MEDLINE    
The placental transfer of beta-adrenoceptor blocking agents has been well established in the last years. Randomized and/or controlled studies have given a less pessimistic view of the consequences of these drugs on the fetal and neonatal adaptation. In fact, the beta-blockers are able to produce hypotension, bradycardia, respiratory troubles in the newborn infant, troubles which are generally slight when the neonates are full-term. However, even if in good clinical conditions, this kind of neonate should be carefully monitored for at least the first 2 days of life.
M J Boutroy
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Developmental pharmacology and therapeutics     Volume:  10     ISSN:  0379-8305     ISO Abbreviation:  Dev Pharmacol Ther     Publication Date:  1987  
Date Detail:
Created Date:  1987-09-10     Completed Date:  1987-09-10     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8003947     Medline TA:  Dev Pharmacol Ther     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  224-31     Citation Subset:  IM    
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MeSH Terms
Adrenergic beta-Antagonists / adverse effects*,  metabolism
Blood Glucose / metabolism
Blood Pressure / drug effects
Fetus / drug effects*,  physiology
Heart Rate / drug effects
Infant, Newborn
Maternal-Fetal Exchange
Respiration / drug effects
Reg. No./Substance:
0/Adrenergic beta-Antagonists; 0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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