| Fetal myocardial morphological and functional changes associated with well-controlled gestational diabetes. | |
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MedLine Citation:
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PMID: 20800336 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To make a global evaluation of the fetal myocardial changes in a well-controlled gestational diabetic population. STUDY DESIGN: Twenty-four pregnant well-controlled diabetic patients were selected. Sixteen normal pregnancies were randomly collected as a control group. Measurements of morphological and functional myocardial parameters were performed. Data from the left ventricular outflow tract and peripheral Doppler data were obtained. RESULT: The thickness of the interventricular septum was increased in diabetic pregnancies (p<0.001). Tricuspid E/A index was the only functional parameter showing a significant variation, with lower values in diabetic pregnancies. Doppler parameters from the left ventricular outflow tract and peripheral Doppler waveforms were similar between groups. CONCLUSION: A tendency towards interventricular septum hypertrophy was observed even in well-controlled diabetic pregnancies. Mild hypertrophic cardiac changes were not associated with abnormal cardiac function or signs of left ventricular outflow obstruction, although minor changes in right ventricular diastolic function were recorded. |
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Authors:
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Jose Garcia-Flores; Mercedes Jañez; Maria Cruz Gonzalez; Nuria Martinez; Mercedes Espada; Antonio Gonzalez |
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Publication Detail:
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Type: Journal Article Date: 2010-08-25 |
Journal Detail:
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Title: European journal of obstetrics, gynecology, and reproductive biology Volume: 154 ISSN: 1872-7654 ISO Abbreviation: Eur. J. Obstet. Gynecol. Reprod. Biol. Publication Date: 2011 Jan |
Date Detail:
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Created Date: 2011-02-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0375672 Medline TA: Eur J Obstet Gynecol Reprod Biol Country: Ireland |
Other Details:
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Languages: eng Pagination: 24-6 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Department of Obstetrics & Gynecology, Quiron Madrid Hospital, C/ Diego de Velazquez 1, 28223 Pozuelo de Alarcon (Madrid), Spain. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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