| Fetal methylmercury exposure as measured by cord blood mercury concentrations in a mother-infant cohort in Hong Kong. | |
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MedLine Citation:
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PMID: 16962662 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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This study was designed to examine newborn infants in Hong Kong prenatally exposed to levels of methylmercury considered to increase risk of neurotoxic effects and to examine subject characteristics that modify the degree of prenatal mercury exposure. Mercury concentrations in 1057 sets of maternal and cord blood samples and 96 randomly selected maternal hair samples were measured. Subject characteristics were measured or collected by questionnaire. Of the 1057 cord blood samples collected only 21.6% had mercury concentrations less than 29 nmol/L (5.8 micro g/L). Median maternal hair mercury concentration was 1.7 ppm. The geometric mean cord to maternal blood mercury ratio was 1.79 to 1. Increasing maternal fish consumption and maternal age were found to be associated with increased cord blood mercury concentrations. Marine fish consumption increased cord blood mercury concentrations more than freshwater fish (5.09%/kg vs 2.86%/kg). Female babies, maternal alcohol consumption and increasing maternal height were associated with decreased cord blood mercury concentrations. Pregnant women in Hong Kong consume large amounts of fish and as a result, most of their offspring have been prenatally exposed to moderately high levels of mercury. In this population, pregnant women should choose freshwater over marine fish and limit fish consumption. |
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Authors:
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Tai F Fok; Hugh S Lam; Pak C Ng; Alexander S K Yip; Ngai C Sin; Iris H S Chan; Goldie J S Gu; Hung K So; Eric M C Wong; Christopher W K Lam |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2006-09-08 |
Journal Detail:
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Title: Environment international Volume: 33 ISSN: 0160-4120 ISO Abbreviation: Environ Int Publication Date: 2007 Jan |
Date Detail:
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Created Date: 2006-12-20 Completed Date: 2007-03-28 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7807270 Medline TA: Environ Int Country: United States |
Other Details:
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Languages: eng Pagination: 84-92 Citation Subset: IM |
Affiliation:
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Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong. taifaifok@cuhk.edu.hk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Female Fetal Blood / chemistry* Fishes Food Contamination Hong Kong Humans Infant, Newborn Male Maternal Exposure* Maternal-Fetal Exchange* Mercury / blood* Methylmercury Compounds* / toxicity Pregnancy Random Allocation Water Pollutants, Chemical / toxicity |
| Chemical | |
Reg. No./Substance:
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0/Methylmercury Compounds; 0/Water Pollutants, Chemical; 7439-97-6/Mercury |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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