Document Detail


Fetal marrow suppression after maternal chemotherapy for leukaemia.
MedLine Citation:
PMID:  7529655     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A preterm baby, whose mother received chemotherapy for acute leukaemia during pregnancy, required intensive care because of profound anaemia and neutropenia. Haemopoietic progenitor cell studies showed fetal marrow suppression. Those caring for such mothers and babies should know the possible serious effects chemotherapy for malignancies can have on a developing fetus. Long term follow up of the baby is imperative.
Authors:
N A Murray; D Acolet; M Deane; J Price; I A Roberts
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  71     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  1994 Nov 
Date Detail:
Created Date:  1995-02-16     Completed Date:  1995-02-16     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  F209-10     Citation Subset:  AIM; IM    
Affiliation:
Department of Haematology, Royal Postgraduate Medical School, Hammersmith Hospital, London.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Anemia / chemically induced*,  therapy
Antineoplastic Combined Chemotherapy Protocols / adverse effects*
Erythropoietin / therapeutic use
Etoposide / adverse effects
Female
Granulocyte Colony-Stimulating Factor / therapeutic use
Humans
Infant, Newborn
Infant, Premature, Diseases / chemically induced*,  therapy
Leukemia, Myeloid / drug therapy*
Neutropenia / chemically induced*,  therapy
Pregnancy
Pregnancy Complications, Neoplastic / drug therapy*
Prenatal Exposure Delayed Effects*
Chemical
Reg. No./Substance:
11096-26-7/Erythropoietin; 143011-72-7/Granulocyte Colony-Stimulating Factor; 33419-42-0/Etoposide
Comments/Corrections

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