Document Detail

Fetal loss after early detection of heart motion in infertility patients. Prognostic factors.
MedLine Citation:
PMID:  9564645     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To evaluate the incidence and prognosticators of spontaneous abortion (< 20 weeks' gestation) in an infertile population after early documentation of fetal cardiac activity. STUDY DESIGN: Retrospective chart review. We examined the incidence of spontaneous abortion in 231 clinical pregnancies with 259 fetuses documented to be viable by transvaginal sonography 28-38 days after ovulation. The population was an unselected group of infertility patients with no history of recurrent pregnancy loss. Maternal age and presence of multiple gestations were analyzed as separate variables by chi 2 testing. RESULTS: The incidence of spontaneous abortion among all fetuses was 9.6% (95% confidence interval [CI], 6.1-13.2%) and among singleton gestations was 7.7% (95% CI, 4.0-11.3%). Women with multiple gestations were more likely to suffer spontaneous fetal loss as compared to women with singleton gestations (18 vs. 7.6%, P < .05). In addition, women aged 35 and above with singleton pregnancies showed a significantly increased rate of fetal loss (13.4 vs. 4.9%, P < .05) when compared with younger women. CONCLUSION: Women > or = 35 years old and those with multiple gestations were significantly more likely to suffer late first- or early second-trimester fetal loss even after detection of fetal cardiac activity. These patients should be counseled differently than younger women with singleton pregnancies, and increased monitoring may be indicated.
J A Keenan; S Rizvi; M R Caudle
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  43     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-06-04     Completed Date:  1998-06-04     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  199-202     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Tennessee Medical Center, Knoxville, TN 37920-6999, USA.
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MeSH Terms
Abortion, Spontaneous / epidemiology*
Age Factors
Fetal Death*
Heart Rate, Fetal
Infertility / therapy*
Pregnancy, Multiple
Retrospective Studies
Risk Assessment

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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