Document Detail

Fetal intracardiac echogenic foci: does it matter which ventricle?
MedLine Citation:
PMID:  9514163     Owner:  NLM     Status:  MEDLINE    
We sought to determine whether an association exists between the location of intracardiac echogenic foci and fetal aneuploidy or structural cardiac lesions. A search of the English language literature since 1980 revealed nine studies reporting location of intracardiac echogenic foci, fetal chromosomal abnormalities, and cardiac anomalies. Aneuploidy was noted in 10 of 217 fetuses with left ventricular and in one of 18 with right ventricular intracardiac echogenic foci. Three of 11 fetuses with biventricular intracardiac echogenic foci were aneuploid, which is significantly more frequently than when intracardiac echogenic foci were present in either ventricle alone (P = 0.02). There were nine cases of trisomy 21, four of trisomy 13, and one of trisomy 18. Structural cardiac lesions were recognized in eight of 217 fetuses with left ventricular foci, two of 18 with right ventricular foci, and one of 11 with biventricular intracardiac echogenic foci (P = 0.16). Biventricular intracardiac echogenic foci are more frequently associated with fetal aneuploidy but not structural lesions, as compared to isolated left or right ventricular intracardiac echogenic foci.
J R Wax; C Philput
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  17     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1998 Mar 
Date Detail:
Created Date:  1998-05-07     Completed Date:  1998-05-07     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  141-4; quiz 145-6     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Hartford Hospital, Connecticut 06102-5037, USA.
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MeSH Terms
Fetal Diseases / ultrasonography
Heart Defects, Congenital / genetics,  ultrasonography*
Heart Ventricles / ultrasonography*
Ultrasonography, Prenatal*

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