Document Detail

Fetal infection after maternal reinfection with rubella: criteria for defining reinfection.
MedLine Citation:
PMID:  2508917     Owner:  NLM     Status:  MEDLINE    
Five cases of asymptomatic maternal reinfection with rubella are described that occurred in England and Wales during 1985-8 and resulted in intrauterine infection. The criteria for diagnosing reinfection are described. In four cases the rubella contact was with the woman's own children. Two women had therapeutic abortions, rubella virus being recovered from the products of conception, and three were delivered of infants with congenitally acquired disease. Though the risks associated with maternal reinfection with rubella are very small and being measured in a prospective study, it is hoped that the recently introduced augmented programme of rubella vaccination will reduce rubella in the community and therefore this small risk still further.
J M Best; J E Banatvala; P Morgan-Capner; E Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  BMJ (Clinical research ed.)     Volume:  299     ISSN:  0959-8138     ISO Abbreviation:  BMJ     Publication Date:  1989 Sep 
Date Detail:
Created Date:  1989-12-12     Completed Date:  1989-12-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8900488     Medline TA:  BMJ     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  773-5     Citation Subset:  AIM; IM    
Department of Virology, United Medical and Dental School, Guy's Hospital, London.
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MeSH Terms
Fetal Diseases / etiology*
Immunoglobulin M / analysis
Infant, Newborn
Maternal-Fetal Exchange
Pregnancy Complications, Infectious* / diagnosis,  immunology
Risk Factors
Rubella / diagnosis,  immunology,  transmission*
Rubella Syndrome, Congenital / etiology
Reg. No./Substance:
0/Immunoglobulin M
Comment In:
BMJ. 1989 Nov 11;299(6709):1217   [PMID:  2513059 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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