Document Detail

Fetal growth restriction associated with measles virus infection during pregnancy.
MedLine Citation:
PMID:  15841617     Owner:  NLM     Status:  MEDLINE    
We report on a 28-week infant with growth restriction starting after 23 weeks' gestation because of measles virus (MV) infection of the mother. Histological findings for the placenta revealed extensive fibrin deposition and necrosis of the villi, and MV antigen was demonstrated in the syncytiotrophoblast by immunostaining. The MV-specific IgM level in the infant was negative, but that of the mother was positive. Therefore, we speculate that growth restriction is not attributed to direct infection with MV, but to placental dysfunction due to a decrease in intravillous blood flow and oxygen supply to the fetus.
Kosuke Kobayashi; Makiko Tajima; Satoshi Toishi; Ken Fujimori; Yoshio Suzuki; Hideo Udagawa
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  33     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2005  
Date Detail:
Created Date:  2005-04-21     Completed Date:  2005-05-19     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  67-8     Citation Subset:  IM    
Department of Obstetrics and Gynecology, Asahi General Hospital, Asahi-shi, Chiba, Japan.
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MeSH Terms
Diagnosis, Differential
Fetal Growth Retardation / complications,  diagnosis*,  pathology,  ultrasonography
Infant, Newborn
Measles / complications,  diagnosis*,  pathology
Pregnancy Complications, Infectious / diagnosis*,  pathology
Pregnancy Trimester, Second
Ultrasonography, Prenatal

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