Document Detail

Fetal gender ratio in recurrent miscarriages.
MedLine Citation:
PMID:  21845066     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: The purpose of this study was to evaluate the gender ratio and incidence of chromosomal anomalies in the products of conception (POC) from recurrent miscarriages.
METHODS: We determined the karyotypes of POC from patients with recurrent spontaneous miscarriages between 1999 and 2009.
RESULTS: In total, 313 specimens were successfully karyotyped, with a median gestational age of 10 weeks at miscarriage (interquartile range 8-13); 199 (64%) were females and 114 (36%) were males. In total, 121 (39%) had abnormal karyotypes, the most prevalent of which were chromosome 21 and 16 trisomies, triploidy, and monosomy X.
CONCLUSION: Our findings suggest that female POC might be more susceptible to recurrent miscarriages than male ones during embryogenesis, implantation, and initial fetal development.
Anna Del Fabro; Lorenza Driul; Omar Anis; Ambrogio P Londero; Serena Bertozzi; Livio Bortotto; Diego Marchesoni
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Publication Detail:
Type:  Journal Article     Date:  2011-07-20
Journal Detail:
Title:  International journal of women's health     Volume:  3     ISSN:  1179-1411     ISO Abbreviation:  Int J Womens Health     Publication Date:  2011  
Date Detail:
Created Date:  2011-08-16     Completed Date:  2011-11-10     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101531698     Medline TA:  Int J Womens Health     Country:  New Zealand    
Other Details:
Languages:  eng     Pagination:  213-7     Citation Subset:  -    
Clinic of Obstetrics and Gynecology.
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