Document Detail


Fetal exposure to gestational diabetes contributes to subsequent adult metabolic syndrome.
MedLine Citation:
PMID:  20430355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Obesity and diabetes have become globally epidemic. The cause of this unprecedented rise in obesity is multifactorial, with inactivity, excessive calorie intake, and genetic factors implicated. More recent data indicate that exposure to diabetes during pregnancy increases the risk of childhood and adult obesity, diabetes, and cardiovascular disease. Evidence derived from recent randomized controlled trials indicates that gestational diabetes mellitus (GDM) treatment reduces newborn obesity and therefore may contribute to reducing the global prevalence of obesity and metabolic syndrome. Current evidence detailing increases in global prevalence of obesity was reviewed together with data evaluating the effectiveness of treatment of GDM. Development of new protocols for diagnosis and treatment of GDM may reduce population obesity and cardiovascular disease.
Authors:
Thomas R Moore
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-04-28
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  202     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-05-31     Completed Date:  2010-06-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  643-9     Citation Subset:  AIM; IM    
Copyright Information:
Copyright 2010 Mosby, Inc. All rights reserved.
Affiliation:
Department of Reproductive Medicine, University of California San Diego, School of Medicine, San Diego, CA, USA.
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MeSH Terms
Descriptor/Qualifier:
Adult
Diabetes, Gestational / epidemiology*,  metabolism
Female
Humans
Metabolic Syndrome X / epidemiology*,  etiology,  metabolism
Obesity / epidemiology*,  etiology,  metabolism
Pregnancy
Prenatal Exposure Delayed Effects / epidemiology*,  metabolism*
Prevalence

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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