Document Detail

Fetal exomphalos at 11 to 14 weeks of gestation.
MedLine Citation:
PMID:  7474053     Owner:  NLM     Status:  MEDLINE    
In an ultrasonographic screening study at 11 to 14 weeks' gestation involving 9885 singleton pregnancies, the prevalence of exomphalos was 0.11% (11 cases) and the prevalence of trisomy 18 or 13 was 0.35% (35 cases). The mean maternal age of the screened population was 35 years (range, 15 to 47 years) and a significant association was found between maternal age and both the prevalence of trisomies and the prevalence of exomphalos. Because the frequency of exomphalos in fetuses with trisomy 18 or 13 was 17% and in those with no evidence of these trisomies it was 0.05%, the risk for trisomies in fetuses with exomphalos is 340 times higher than in those without exomphalos.
R J Snijders; M L Brizot; M Faria; K H Nicolaides
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  14     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  1995 Aug 
Date Detail:
Created Date:  1995-12-14     Completed Date:  1995-12-14     Revised Date:  2004-11-18    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  569-74     Citation Subset:  IM    
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital Medical School, London, United Kingdom.
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MeSH Terms
Chromosome Aberrations / epidemiology*,  ultrasonography
Chromosome Disorders
Chromosomes, Human, Pair 13*
Chromosomes, Human, Pair 18*
Fetal Diseases / epidemiology*,  genetics,  ultrasonography
Hernia, Umbilical / epidemiology*,  genetics,  ultrasonography
Infant, Newborn
Mass Screening
Maternal Age
Pregnancy Trimester, First
Pregnancy, High-Risk
Prospective Studies
Risk Factors
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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