Document Detail

Fetal evaluation of the modified-myocardial performance index in pregnancies complicated by diabetes.
MedLine Citation:
PMID:  22825924     Owner:  NLM     Status:  Publisher    
OBJECTIVE: To evaluate the fetal cardiac function by modified myocardial performance index (Mod-MPI) in pregnant diabetic patients. METHODS: Modified myocardial performance index was measured in fetuses of patients with diabetes (DM) between 30 and 40 weeks of gestation. The isovolumetric contraction time, isovolumetric relaxation time and ejection time were measured. Mod-MPI was calculated as (isovolumetric contraction time + isovolumetric relaxation time)/ejection time. Results were analyzed by using one-way analysis of variance (post hoc Bonferroni correction), Chi-square and Student's test. RESULTS: Modified myocardial performance index values of fetuses from DM mothers were significantly higher than controls (0.43 vs 0.37, P < 0.0001), and it was not different between gestational versus pregestational DM (0.42 vs 0.45, P = 0.18). Mod-MPI was also higher in the presence of polyhydramnios (0.49 vs 0.41, P < 0.0001), insulin use (0.46 vs 0.40, P < 0.05), and large for gestational age fetuses (0.49 vs 0.40, P < 0.0001). There were no significant differences in Mod-MPI between newborns with versus without neonatal complications such as hypoglycemia or polycythemia. CONCLUSIONS: In fetuses of DM mothers, evaluation of the Mod-MPI identifies those with worse maternal disease and large fetal size. © 2012 John Wiley & Sons, Ltd.
Horacio Figueroa; Maria Carolna Silva; Cristian Kottmann; Sebastian Viguera; Ignacio Valenzuela; Edgar Hernandez-Andrade; Eduard Gratacos; Jose Antonio Arraztoa; Sebastián E Illanes
Related Documents :
12817504 - Expression of the uterine mx protein in cyclic and pregnant cows, gilts, and mares.
16726424 - Fertility and hormonal responses to temporary relief of heat stress in lactating dairy ...
8778094 - Effect of a gonadotropin-releasing hormone agonist on follicle recruitment and pregnanc...
16962164 - Evaluation of intrauterine antibiotic treatment of clinical metritis and retained fetal...
16254884 - Z-velocity in screening for intrauterine growth restriction.
7095244 - Effect of angiotensin infusion during pregnancy on fetal heart rate and on fetal activity.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-7-24
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  -     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-7-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-6     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons, Ltd.
Department of Obstetrics & Gynecology and Laboratory of Reproductive Biology, Universidad de Los Andes, Chile; Department of Maternal-Fetal Medicine, Clínica Davila, Santiago, Chile.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cylindrospermopsin determination in water by LC-MS/MS: Optimization and validation of the method and...
Next Document:  A parent-mediated intervention to increase responsive parental behaviors and child communication in ...