Document Detail


Fetal electrocardiogram ST-segment analysis and prediction of neonatal acidosis.
MedLine Citation:
PMID:  17368461     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To determine the diagnostic value of fetal ST-segment analysis (STAN) in predicting neonatal acidosis. METHODS: The STAN S21 was used to monitor singleton fetuses in labor with abnormal FHR. Physicians later reviewed tracings to identify any ST events dictating intervention. Outcome measures were umbilical artery pH< or =7.15 and pH< or =7.05 at birth. The sensitivity, specificity, PPV, and NPV of a significant ST event to predict both outcomes were calculated. RESULTS: Analysis included 411 women. Sensitivity of a significant ST event for screening pH< or =7.15 (21.9%) was 38% (41/108), specificity 83% (252/303), PPV 45% (41/92) and NPV 79% (252/319), and for pH< or =7.05, it was (3.4%), 62.5% (10/16), 79% (313/395), 11% (10/92), and 98% (313/319), respectively. CONCLUSION: In a population with abnormal FHR in labor, STAN sensitivity is moderate (almost 40%) for predicting pH< or =7.15 and better (almost 60%) for more severe acidosis (pH< or =7.05).
Authors:
C Vayssiere; R Haberstich; V Sebahoun; E David; E Roth; B Langer
Publication Detail:
Type:  Evaluation Studies; Journal Article; Multicenter Study     Date:  2007-03-26
Journal Detail:
Title:  International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics     Volume:  97     ISSN:  0020-7292     ISO Abbreviation:  Int J Gynaecol Obstet     Publication Date:  2007 May 
Date Detail:
Created Date:  2007-04-23     Completed Date:  2007-08-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0210174     Medline TA:  Int J Gynaecol Obstet     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  110-4     Citation Subset:  IM    
Affiliation:
Département de Gynécologie-Obstétrique, CHU de Hautepierre, Strasbourg cedex, France. cvayssiere@club-internet.fr
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MeSH Terms
Descriptor/Qualifier:
Acidosis / diagnosis*
Biological Markers
Electrocardiography*
False Negative Reactions
False Positive Reactions
Female
Fetal Blood / physiology*
Fetal Distress / diagnosis*,  physiopathology
Fetal Monitoring / methods*
Fetus / physiology*
Humans
Infant, Newborn
Predictive Value of Tests
Pregnancy
Chemical
Reg. No./Substance:
0/Biological Markers

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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