Document Detail

Fetal dose for a patient undergoing mantle field irradiation for Hodgkin's disease.
MedLine Citation:
PMID:  9243468     Owner:  NLM     Status:  MEDLINE    
In order to safely treat a 23 weeks pregnant woman for supradiapharagmatic Hodgkin's disease, without compromising the fetus, a custom shielding table was constructed and extensive phantom measurements were performed. For 10 MV photons, the optimal shielding combination was found to consist of a 5 cm thick lead sheet placed onto a 1.25 cm aluminum supporting plate. The structure was placed directly above the phantom, over the region corresponding to the woman's abdomen, without any intervening air gap. By this means the dose to the fetus from machine leakage and collimator scatter was eliminated; the only remaining dose was due to in-phantom scatter. The woman was treated using a mantle field to a dose of 35 Gy in 20 fractions. The accumulated dose to the woman's uterine fundus and to her pubis were monitored with theroluminescent dosimeters. After completion of mantle therapy the doses to the fundus and pubis were 10 and 3 cGy, respectively. The fetal exposure was thus limited to below 10 cGy, within the zone of fetal tolerance. A normal infant was delivered at term.
J Cygler; G X Ding; W Kendal; P Cross
Related Documents :
19944798 - Pregnancy and inflammatory bowel disease.
8672028 - Repeated successful pregnancies after kidney transplantation in 102 women (report by th...
6407728 - Classics in oncology. survey of current opinions concerning carcinoma of the breast occ...
7368978 - Familial occurrence of the haemolytic uraemic syndrome.
3646338 - Prolonged receptivity to the male and the fate of spermatozoa in the female black masti...
19432998 - Reduced expression of crh receptor type 1 in upper segment human myometrium during labour.
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical dosimetry : official journal of the American Association of Medical Dosimetrists     Volume:  22     ISSN:  0958-3947     ISO Abbreviation:  Med Dosim     Publication Date:  1997  
Date Detail:
Created Date:  1997-09-16     Completed Date:  1997-09-16     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8908862     Medline TA:  Med Dosim     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  135-7     Citation Subset:  IM    
Medical Physics Department, Ottawa Regional Cancer Centre, Ontario, Canada.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Fetus / radiation effects*
Hodgkin Disease / radiotherapy*
Phantoms, Imaging
Pregnancy Complications, Neoplastic / radiotherapy*
Radiation Protection
Radiotherapy Dosage
Thermoluminescent Dosimetry

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Dosimetric analysis and clinical implementation of 6 MV X-ray radiosurgery beam.
Next Document:  Midline shield for radiation therapy of carcinoma of the uterine cervix: should it be "midline" or "...