Document Detail

Fetal distress associated with the anticardiolipin antibody and a history of intrauterine fetal demise. A case report.
MedLine Citation:
PMID:  2715994     Owner:  NLM     Status:  MEDLINE    
A woman with a history of fetal demise, an elevated anticardiolipin antibody titer, lupus anticoagulant but no evidence of systemic lupus erythematosus received anticoagulation with heparin in adjusted subcutaneous doses. Daily fetal monitoring demonstrated reactive nonstress tests and normal biophysical profiles initially. At 30 weeks' gestation, however, repeated spontaneous decelerations developed, and fetal bradycardia necessitated delivery. The combination of a poor obstetric history and the presence of high cardiolipin antibody titers requires close fetal surveillance. The benefits of anticoagulation in this setting deserve further study.
J S Greenspoon; D Buchanan
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The Journal of reproductive medicine     Volume:  34     ISSN:  0024-7758     ISO Abbreviation:  J Reprod Med     Publication Date:  1989 Apr 
Date Detail:
Created Date:  1989-06-14     Completed Date:  1989-06-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0173343     Medline TA:  J Reprod Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  311-4     Citation Subset:  IM    
Department of Obstetrics and Gynecology, University of Southern California School of Medicine.
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MeSH Terms
Antibodies / analysis*
Cardiolipins / immunology*
Fetal Death / prevention & control*
Fetal Distress / drug therapy,  etiology*
Fetal Monitoring
Heparin / administration & dosage,  therapeutic use
Injections, Subcutaneous
Reg. No./Substance:
0/Antibodies; 0/Cardiolipins; 9005-49-6/Heparin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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