Document Detail


Fetal demise due to herpes simplex virus: an illustrated case report.
MedLine Citation:
PMID:  11840250     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report and illustrate a case of fetal demise at 31 weeks caused by fulminant herpes simplex virus (HSV) infection. The 15-year-old mother reported no past history or symptoms of an HSV infection during pregnancy. Autopsy revealed extensively ulcerated skin and necrosis of the liver, adrenal glands, brain, and placental membranes. Fluorescent in situ hybridization studies of the lungs, liver, adrenal glands and placenta were positive for HSV, but did not distinguish between HSV-1 and HSV-2. A maternal postpartum blood sample was positive for HSV-2 by immunoblot assay.
Authors:
Katharine H Barefoot; George A Little; Kim T Ornvold
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatology : official journal of the California Perinatal Association     Volume:  22     ISSN:  0743-8346     ISO Abbreviation:  J Perinatol     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-02-12     Completed Date:  2002-03-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8501884     Medline TA:  J Perinatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  86-8     Citation Subset:  IM    
Affiliation:
Dartmouth Medical School, Hanover, NH 03756, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Fatal Outcome
Female
Herpes Genitalis / transmission*
Humans
Immunohistochemistry
Infant, Newborn
Infectious Disease Transmission, Vertical*
Liver / pathology
Necrosis
Pregnancy
Pregnancy Complications, Infectious*
Skin Ulcer / virology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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