Document Detail

Fetal cystic adenomatoid malformation of the lung: apparent improvement in utero.
MedLine Citation:
PMID:  3287247     Owner:  NLM     Status:  MEDLINE    
Fetal cystic adenomatoid malformation is a rare pulmonary abnormality, usually involving only a part of the lung, that is characterized by excessive growth of the terminal respiratory elements. The natural history of this lesion and hence the prognosis after antenatal detection is still unclear. We report two cases of large cystic adenomatoid malformation, diagnosed prenatally, in which the size of the mass diminished visibly during the third trimester. Both fetuses had excellent outcomes after surgery. These findings suggest that when a cystic adenomatoid malformation is diagnosed antenatally, the initial impression concerning the size of the mass and final prognosis may not necessarily predict outcome, because there may be improvement during fetal life.
D H Saltzman; N S Adzick; B R Benacerraf
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  71     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-06-27     Completed Date:  1988-06-27     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1000-2     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Brigham and Women's Hospital, Boston, Massachusetts.
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MeSH Terms
Infant, Newborn
Lung / abnormalities*,  pathology,  surgery
Pregnancy Trimester, Third
Prenatal Diagnosis

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