Document Detail

Fetal cleft lip with and without cleft palate: Comparison between MR imaging and US for prenatal diagnosis.
MedLine Citation:
PMID:  20418035     Owner:  NLM     Status:  In-Data-Review    
OBJECTIVE: To describe the magnetic resonance (MR) imaging findings of fetal CL/CP and evaluate its diagnostic value.
METHODS AND MATERIALS: Twelve fetuses with CL/CP diagnosed by transabdominal US underwent MR imaging within 2 days of US. Half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence on T2-weighted images was performed on sagittal, coronal, and axial planes anatomic to the fetuses during maternal breath holding. US and MR imaging findings were compared with final diagnoses obtained from post-natal physical examination or fetal autopsy.
RESULTS: Final diagnoses confirmed incomplete midline cleft lip (n=1), unilateral cleft lip and palate (n=7), bilateral cleft lip and palate (n=1), midline cleft lip and palate (n=3). US and MR imaging diagnosed all 12 fetuses with cleft lip and the laterality. 5 (45.5%) of 11 cleft palates were identified with US, 2 of 7 fetuses with unilateral cleft palate, 2 of 3 fetuses with midline cleft palate, and one fetus with bilateral cleft palate. On MR imaging, 10 (91%) of 11 cleft palates were correctly detected. One fetus with unilateral cleft palate was not detected. No false-positives occurred.
CONCLUSION: MR imaging is valuable for diagnosis of fetal CL/CP. It can demonstrate additional findings and provide more information compared with US.
Guangbin Wang; Ruiqin Shan; Lianxin Zhao; Xiangyu Zhu; Xinjuan Zhang
Related Documents :
21463705 - Positron emission tomography in patients with suspected pacing system infections may pl...
15253055 - Watershed infarcts in the fetal and neonatal brainstem. an aetiology of central hypoven...
10067925 - Anatomical and embryological considerations in the repair of a large vertex cephalocele...
9316055 - A magnetic resonance template for normal cerebellar development in the human fetus.
21478995 - High finesse microfiber knot resonators made from double-ended tapered fibers.
19380545 - Diagnosis of osteomyelitis in children: utility of fat-suppressed contrast-enhanced mri.
Publication Detail:
Type:  Journal Article     Date:  2010-04-24
Journal Detail:
Title:  European journal of radiology     Volume:  79     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  437-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Shandong Medical Imaging Research Institute, 324 Jingwu Road, Jinan, 250021, China.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The HER3/ErbB3 receptor: A promising target in cancer drug therapy.
Next Document:  MDCT angiography assessment of renal artery in-stent restenosis: Can we reduce the radiation exposur...