Document Detail


Fetal cleft lip with and without cleft palate: Comparison between MR imaging and US for prenatal diagnosis.
MedLine Citation:
PMID:  20418035     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
OBJECTIVE: To describe the magnetic resonance (MR) imaging findings of fetal CL/CP and evaluate its diagnostic value.
METHODS AND MATERIALS: Twelve fetuses with CL/CP diagnosed by transabdominal US underwent MR imaging within 2 days of US. Half-Fourier acquisition single-shot turbo spin echo (HASTE) sequence on T2-weighted images was performed on sagittal, coronal, and axial planes anatomic to the fetuses during maternal breath holding. US and MR imaging findings were compared with final diagnoses obtained from post-natal physical examination or fetal autopsy.
RESULTS: Final diagnoses confirmed incomplete midline cleft lip (n=1), unilateral cleft lip and palate (n=7), bilateral cleft lip and palate (n=1), midline cleft lip and palate (n=3). US and MR imaging diagnosed all 12 fetuses with cleft lip and the laterality. 5 (45.5%) of 11 cleft palates were identified with US, 2 of 7 fetuses with unilateral cleft palate, 2 of 3 fetuses with midline cleft palate, and one fetus with bilateral cleft palate. On MR imaging, 10 (91%) of 11 cleft palates were correctly detected. One fetus with unilateral cleft palate was not detected. No false-positives occurred.
CONCLUSION: MR imaging is valuable for diagnosis of fetal CL/CP. It can demonstrate additional findings and provide more information compared with US.
Authors:
Guangbin Wang; Ruiqin Shan; Lianxin Zhao; Xiangyu Zhu; Xinjuan Zhang
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Publication Detail:
Type:  Journal Article     Date:  2010-04-24
Journal Detail:
Title:  European journal of radiology     Volume:  79     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-30     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  437-42     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Elsevier Ireland Ltd. All rights reserved.
Affiliation:
Shandong Medical Imaging Research Institute, 324 Jingwu Road, Jinan, 250021, China.
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