Document Detail


Fetal cells in a transcervical cell sample collected at 5 weeks of gestation.
MedLine Citation:
PMID:  16318979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Transcervical cell (TCC) sampling is being investigated as a promising method for obtaining fetal cells for prenatal genetic diagnosis. The present case report describes the identification of fetal cells by both fluorescent in situ hybridisation (FISH) and quantitative fluorescent polymerase chain reaction (QF-PCR) analyses in a TCC sample collected by intrauterine lavage at 5 + 0 weeks. This finding underscores the possible relevance of TCC sampling for extremely early prenatal genetic diagnosis.
Authors:
Riccardo Cioni; Cecilia Bussani; Sandra Bucciantini; Gianfranco Scarselli
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians     Volume:  18     ISSN:  1476-7058     ISO Abbreviation:  J. Matern. Fetal. Neonatal. Med.     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-12-01     Completed Date:  2006-04-11     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  101136916     Medline TA:  J Matern Fetal Neonatal Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  271-3     Citation Subset:  IM    
Affiliation:
Department of Gynecology, Perinatology and Human Reproduction, University of Florence, Careggi University Hospital, Florence, Italy.
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MeSH Terms
Descriptor/Qualifier:
Female
Fetus / cytology*
Fluorescence
Genetic Testing*
Gestational Age
Humans
In Situ Hybridization, Fluorescence
Irrigation*
Placenta / cytology
Polymerase Chain Reaction / methods
Pregnancy
Prenatal Diagnosis / methods*
Sex Determination (Genetics)
Uterus / cytology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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