| Fetal cardiovascular hemodynamics in the presence of complete atrioventricular block. | |
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MedLine Citation:
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PMID: 8178848 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: Our purpose was to follow serially the hemodynamic adaptation to a congenital complete heart block in a human fetus. STUDY DESIGN: Longitudinal and serial M-mode and Doppler echocardiography over a 10-week span were performed on a fetus affected by complete heart block. Ventricular fractional shortening, size, and flow across the atrioventricualr valves and outflow tracts were determined starting at 20 weeks up to the time of delivery. Neonatal Doppler follow-up was performed at 2 days of life after implantation of a temporary pacemaker. RESULTS: The right and left ventricles were able to adapt to sustained bradycardia by increasing their size. This ventricular dilatation was also associated with an increase in fractional shortening, which was associated with ventricualr free wall hypertrophy. When ventricualr heart rate decreased to 38 beats/min, fractional shortening decreased, this was associated with the rapid onset of ascites and pericardial effusion. CONCLUSION: In the presence of sustained bradycardia ventricular output can increase, because this fetus was able to increase ventricular size and fractional shortening and wall thickness. |
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Authors:
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J C Veille; W Covitz |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of obstetrics and gynecology Volume: 170 ISSN: 0002-9378 ISO Abbreviation: Am. J. Obstet. Gynecol. Publication Date: 1994 May |
Date Detail:
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Created Date: 1994-06-09 Completed Date: 1994-06-09 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370476 Medline TA: Am J Obstet Gynecol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 1258-62 Citation Subset: AIM; IM |
Affiliation:
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Department of Obstetrics and Gynecology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, NC 27157. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Echocardiography, Doppler Female Fetal Diseases / pathology, physiopathology* Fetal Heart / ultrasonography Heart Block / pathology, physiopathology* Heart Rate, Fetal* Heart Ventricles / pathology Humans Pregnancy Pregnancy Complications Sjogren's Syndrome / complications Thyroiditis, Autoimmune / complications Ultrasonography, Prenatal Ventricular Function, Left* |
| Grant Support | |
ID/Acronym/Agency:
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HL38296/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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