Document Detail


Fetal cardiac ventricular volume, cardiac output, and ejection fraction determined with 4-dimensional ultrasound using spatiotemporal image correlation and virtual organ computer-aided analysis.
MedLine Citation:
PMID:  21531373     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The objective of this study was to quantify fetal cardiovascular parameters using spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL).
STUDY DESIGN: A cross-sectional study was performed in normal pregnancies (19-42 weeks) to evaluate ventricular volume, stroke volume (SV), cardiac output (CO), and ejection fraction (EF). The CO was also expressed as a function of estimated fetal weight and biometric parameters.
RESULTS: The following results were found: (1) 184 STIC datasets; (2) with advancing gestation, ventricular volume, SV, CO, and adjusted CO increased, whereas EF decreased; (3) right ventricular (RV) volume was larger than the left ventricular (LV) volume in systole (0.50 vs 0.27 mL; P < .001) and diastole (1.20 vs 1.03 mL; P < .001); (4) there were no differences between the LV and RV in SV, CO, or adjusted CO; and (5) LV EF was greater than the RV EF (72.2 vs 62.4%; P < .001).
CONCLUSION: Normal fetal cardiovascular physiology is characterized by a larger RV volume and a greater LV EF, resulting in similar LV and RV SV and CO.
Authors:
Neil Hamill; Lami Yeo; Roberto Romero; Sonia S Hassan; Stephen A Myers; Pooja Mittal; Juan Pedro Kusanovic; Mamtha Balasubramaniam; Tinnakorn Chaiworapongsa; Edi Vaisbuch; Jimmy Espinoza; Francesca Gotsch; Luis F Goncalves; Wesley Lee
Related Documents :
18373663 - Coronary sinus focus acting as a trigger for atrial fibrillation in a patient with orth...
16858233 - Percutaneous left atrial appendage transcatheter occlusion in patients with chronic non...
25454393 - An increased b-type natriuretic peptide in the absence of a cardiac abnormality identi...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Intramural     Date:  2011-04-30
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  205     ISSN:  1097-6868     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-11-17     Completed Date:  2012-01-18     Revised Date:  2013-06-30    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  76.e1-10     Citation Subset:  AIM; IM    
Copyright Information:
Published by Mosby, Inc.
Affiliation:
Perinatology Research Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, MD, and Detroit, MI, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Cardiac Output / physiology*
Echocardiography, Four-Dimensional / instrumentation,  methods*
Female
Fetal Heart / physiology,  ultrasonography
Gestational Age
Humans
Image Processing, Computer-Assisted / instrumentation,  methods*
Organ Size / physiology
Pregnancy
Pregnancy Trimester, Second / physiology
Pregnancy Trimester, Third / physiology
Ultrasonography, Prenatal / methods
Ventricular Function / physiology*
Grant Support
ID/Acronym/Agency:
ZIA HD002401-18/HD/NICHD NIH HHS
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  The role of oxidative stress in the developmental origin of adult hypertension.
Next Document:  Severe early-onset preeclampsia is not associated with a change in placental catechol O-methyltransf...