Document Detail

Fetal cardiac scanning performed immediately following an abnormal nuchal translucency examination.
MedLine Citation:
PMID:  18702103     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: To study the implications of early fetal cardiac scanning immediately following an abnormal nuchal translucency (NT) examination. METHODS: Fetal cardiac scanning was performed immediately after an increased NT was observed. Scans were performed transvaginally at 11 to 14 weeks. Fetal echocardiography was repeated between 14 and 24 weeks in continuing pregnancies, or when the cardiac scanning appeared normal at 11 to 14 weeks. RESULTS: We performed 2513 NT examinations. An abnormal NT was observed in 135 (5.4%) patients. In addition, 65 patients with an abnormal NT were referred to us for fetal cardiac scanning from other offices. Overall, we performed 200 fetal cardiac scans between 11.2 and 13.5 weeks for an abnormal NT examination. Twelve major fetal cardiac anomalies were diagnosed between 12 and 13.5 weeks. Seven patients (58%) terminated pregnancy between 12 and 14 weeks without performing chorionic villous sampling (CVS). Five patients asked for chromosomal analysis before deciding about their pregnancy. Fetal cardiac anomalies were suspected in six additional cases, but only one of them was diagnosed. Another five minor and one major fetal cardiac anomaly were suspected at 11 to 14 weeks but diagnosed later on fetal echocardiography. CONCLUSION: Major fetal cardiac anomalies can be detected immediately following an abnormal NT examination and be useful for the patients' decisions about the management of their pregnancy.
Zeev Weiner; Boris Weizman; Ron Beloosesky; Israel Goldstein; Allan Bombard
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Prenatal diagnosis     Volume:  28     ISSN:  0197-3851     ISO Abbreviation:  Prenat. Diagn.     Publication Date:  2008 Oct 
Date Detail:
Created Date:  2008-10-06     Completed Date:  2009-01-13     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  England    
Other Details:
Languages:  eng     Pagination:  934-8     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2008 John Wiley & Sons, Ltd.
Department of Obstetrics and Gynecology, Rambam Medical Center, Haifa, Israel.
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MeSH Terms
Echocardiography / methods*
Feasibility Studies
Fetal Heart / abnormalities,  ultrasonography*
Middle Aged
Nuchal Translucency Measurement*
Pregnancy Trimester, First
Sensitivity and Specificity
Ultrasonography, Prenatal / methods*
Young Adult

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