Document Detail


Fetal cardiac output and its distribution to the placenta at 11-20 weeks of gestation.
MedLine Citation:
PMID:  18973262     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To measure serial changes in cardiac output (CO) and its fraction distributed to the placenta at 11-20 weeks of gestation. METHODS: Blood flow velocities, and diameters of the aorta, pulmonary artery and umbilical vein, were measured longitudinally in 143 fetuses using pulsed-wave Doppler and two-dimensional ultrasound examination. RESULTS: Volume blood flow of the aorta (left ventricular CO) and the pulmonary artery (right ventricular CO) increased in a similar manner with advancing gestational age. The combined cardiac output (CCO) increased from 9 mL/min to 121 mL/min, and the placental volume blood flow (Q(uv)) increased from 1.2 mL/min to 25.3 mL/min during 11-20 weeks of gestation. The fraction of CCO diverted to the placenta increased from 14% at 11 weeks to 21% at 20 weeks. CONCLUSIONS: We have established longitudinal reference ranges for fetal CO and Q(uv) at 11-20 weeks of gestation. The fraction of CCO distributed to the placenta increased significantly during this period, reflecting rapid placental growth and establishment of a low-resistance circulation.
Authors:
T Vimpeli; H Huhtala; T Wilsgaard; G Acharya
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology     Volume:  33     ISSN:  1469-0705     ISO Abbreviation:  Ultrasound Obstet Gynecol     Publication Date:  2009 Mar 
Date Detail:
Created Date:  2009-03-04     Completed Date:  2010-02-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9108340     Medline TA:  Ultrasound Obstet Gynecol     Country:  England    
Other Details:
Languages:  eng     Pagination:  265-71     Citation Subset:  IM    
Copyright Information:
(c) 2008 ISUOG. Published by John Wiley & Sons, Ltd.
Affiliation:
Central Maternity Unit, City of Tampere, Tampere, Finland.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Algorithms
Aorta / physiology
Blood Flow Velocity / physiology
Cardiac Output / physiology*
Female
Fetal Heart / physiology*,  ultrasonography
Gestational Age
Heart Ventricles / physiopathology,  ultrasonography
Humans
Male
Placenta / blood supply*,  ultrasonography
Pregnancy
Prospective Studies
Pulmonary Artery / physiology
Reproducibility of Results
Ultrasonography, Prenatal / methods
Umbilical Veins / physiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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