| Fetal cardiac malposition: incidence and outcome of associated cardiac and extracardiac malformations. | |
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MedLine Citation:
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PMID: 18401841 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Cardiac malposition is a rare but important finding when detected on fetal ultrasound. The purpose of this study was to evaluate the incidence of fetal cardiac malposition, associated abnormalities, and clinical outcome in a tertiary-care medical center. Records of fetuses (1993 to 2006) with dextroposition, dextrocardia, mesocardia, ectopia cordis, or heterotaxy were reviewed. The presence of congenital heart disease (CHD), extracardiac anomalies, and outcome were noted. Cardiac malposition was present in 101 fetuses among a total of 3313 (3%) pregnancies. In 78 (78%) patients, the heart was positioned in the right hemithorax. Of those, 26 (33%) had dextrocardia (CHD = 21), and 52 (67%) had dextroposition (CHD = 14). Sixteen (16%) patients had mesocardia (CHD = 8), and 7 (7%) had ectopia cordis (CHD = 6). The majority (58%) of fetal cardiac malposition was caused by intrathoracic masses. Concomitant CHD occurred in 50%. Outcome was available in 97%. The perinatal and neonatal mortality rate was 30%; the elective termination rate was 4%. Patients with CHD had higher mortality rates. The highest mortality rates occurred in ectopia cordis and combined disease of diaphragmatic hernia and CHD. |
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Authors:
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Christine B Falkensammer; Nancy A Ayres; Carolyn A Altman; Shuping Ge; Louis I Bezold; Benjamin W Eidem; John P Kovalchin |
Publication Detail:
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Type: Journal Article Date: 2008-04-09 |
Journal Detail:
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Title: American journal of perinatology Volume: 25 ISSN: 0735-1631 ISO Abbreviation: Am J Perinatol Publication Date: 2008 May |
Date Detail:
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Created Date: 2008-05-09 Completed Date: 2008-11-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8405212 Medline TA: Am J Perinatol Country: United States |
Other Details:
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Languages: eng Pagination: 277-81 Citation Subset: IM |
Affiliation:
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Texas Children's Hospital, Baylor College of Medicine, Houston, Texas, USA. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Abortion, Eugenic Adolescent Adult Female Fetal Diseases / epidemiology*, mortality Heart Defects, Congenital / complications, epidemiology*, mortality Hernia, Diaphragmatic / complications Hernia, Umbilical / complications Humans Infant Infant, Newborn Pregnancy Pregnancy Outcome Retrospective Studies Ultrasonography, Prenatal |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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