Document Detail


Fetal cardiac dextroposition in the absence of an intrathoracic mass: sign of significant right lung hypoplasia.
MedLine Citation:
PMID:  11026578     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We reviewed our experience of fetal cardiac dextroposition in the absence of an intrathoracic mass. Ten cases were found by fetal echocardiography to have a normal cardiac axis, but the heart was shifted into the right chest and the amount of right lung tissue was reduced. At birth seven of the infants had confirmed structural heart disease (70%), including three with scimitar syndrome. Two infants had additional extracardiac anomalies (20%). Seven infants born at term had clinical pulmonary hypertension with a diagnosis of right lung hypoplasia in all of them. Two neonates died owing to significant heart disease (one with scimitar syndrome and the other with hypoplastic left heart syndrome). Of the three pregnancies that were terminated, the two fetuses with autopsies had severe right lung hypoplasia. Fetal cardiac dextroposition and right pulmonary artery hypoplasia in the absence of an intrathoracic mass are important signs of right lung hypoplasia, which can be associated with significant pathologic cardiac and extracardiac conditions.
Authors:
M M Abdullah; R V Lacro; J Smallhorn; D Chitayat; M E van der Velde; S J Yoo; L Oman-Ganes; L K Hornberger
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine     Volume:  19     ISSN:  0278-4297     ISO Abbreviation:  J Ultrasound Med     Publication Date:  2000 Oct 
Date Detail:
Created Date:  2001-02-05     Completed Date:  2001-02-08     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8211547     Medline TA:  J Ultrasound Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  669-76     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, Division of Cardiology, The Hospital for Sick Children and the University of Toronto, Ontario, Canada.
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MeSH Terms
Descriptor/Qualifier:
Dextrocardia / complications,  embryology,  ultrasonography*
Female
Humans
Lung / abnormalities*,  embryology,  ultrasonography
Pregnancy
Retrospective Studies
Ultrasonography, Prenatal*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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