Document Detail

Fetal breathing movements and lung hypoplasia: preliminary human observations.
MedLine Citation:
PMID:  3976753     Owner:  NLM     Status:  MEDLINE    
Hypoplasia of the fetal lung is found in association with long-standing oligohydramnios. In animal models, interference with fetal breathing activity has led to lung hypoplasia. It has been suggested that lung hypoplasia associated with oligohydramnios is due to inhibition of fetal breathing. Observations of seven patients with prolonged oligohydramnios, three of whom had lung hypoplasia, indicate that fetal breathing does occur in these cases and that is unlikely that lung hypoplasia is merely the result of absent fetal breathing activity. In fact, when compared to the four patients with oligohydramnios and presumably normal lungs, the three patients with oligohydramnios and lung hypoplasia spent more time breathing and did so at higher rates.
H E Fox; A C Moessinger
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  151     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-04-01     Completed Date:  1985-04-01     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  531-3     Citation Subset:  AIM; IM    
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MeSH Terms
Amniotic Fluid / physiology
Fetal Movement
Fetus / physiology*
Lung / abnormalities*,  embryology
Pregnancy Trimester, Third
Grant Support

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